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MMAF
An auristatin with anticancer activity
Triclabendazole
A benzimidazole anthelmintic
Cytochalasin J
An inhibitor of actin polymerization
Epothilone A
An antimicrotubule agent
CYT997 (Lexibulin)
An inhibitor of microtubule polymerization
Vincristine sulfate
An antimitotic inhibitor of tubulin polymerization
Cabazitaxel
A semisynthetic taxane
Cevipabulin
An activator of microtubule polymerization
Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium
A potent inhibitor of tubulin polymerization
Ferulenol
A prenylated 4-hydroxycoumarin
D-64131
An inhibitor of tubulin polymerization
Docetaxel Trihydrate
Docetaxel Trihydrate (RP-56976 Trihydrate) 是一种抗肿瘤剂,可抑制微管解聚,IC50 值为 0.2 μM。 Docetaxel Trihydrate 是紫杉醇的半合成类似物,可减弱 bcl-2 和 bcl-xL 基因表达的影响。 Docetaxel Trihydrate 在 G2/M 停止细胞周期并导致细胞凋亡。
Colchicine
Griseofulvin
A fungal metabolite with antifungal and anticancer activities
Vinflunine Tartrate
Etanercept is an inhibitor of the inflammatory factor TNF-α and is mainly used for the clinical treatment of rheumatoid arthritis .