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UNC2025 hydrochloride
An orally bioavailable inhibitor of Mer and Flt3
TCS 359
A cell-permeable FLT3 inhibitor
5'-Fluoroindirubinoxime
An inhibitor of FLT3 kinase
Dovitinib Dilactic acid
FLT3 inhibitor
Tandutinib (MLN518)
An antagonist of PDGFRβ, FLT3, and c-Kit
SKLB4771 (FLT3-IN-1)
SKLB4771 is a potent and selective inhibitor of human receptor-type tyrosine-protein kinase FLT3 with IC50 of 10?nM.
G-749
An FLT3 kinase inhibitor
TAK-659
TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
Quizartinib (AC220)
An inhibitor of FLT3
FLT3-IN-1
FF-10101 is a novel irreversible FLT3 inhibitor with ic50 of 0.20 nM and 0.16 nM for FLT3 (WT) and FLT3(D835Y), respectively.
FLT3-IN-1 Succinate
FLT3-IN-1Succinate是有效地FLT3抑制剂,来自专利WO2015056683A1,化合物实例A。
FLT3-IN-2
An inhibitor of FLT3, c-Kit, and c-FMS
FLT3 Inhibitor III
A potent, highly selective inhibitor of FLT3
UNC2025
UNC2541
UNC2541 is a potent and specific inhibitor of Mer tyrosine kinase (MerTK) that binds in the MerTK ATP pocket with IC50 of 4.4 nM. UNC2541 inhibits phosphorylated MerTK (pMerTK) with EC50 of 510 nM.