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GRL0617
A SARS-CoV and SARS-CoV-2 PLpro inhibitor
6RK73
6RK73 是一种共价不可逆的特异性 UCHL1 抑制剂,IC50 为 0.23 µM。6RK73 对 UCHL3 几乎没有抑制效果 (IC50=236 µM)。6RK73 特异性抑制乳腺癌中 UCHL1 的活性。
STD1T
An inhibitor of USP2a
P 22077
P 22077 是一种可渗透细胞的泛素特异性蛋白酶 7 (USP7) 抑制剂,EC50 为 8.01 μM。 P 22077 还抑制 USP47,EC50 为 8.74 μM。
WP1130
A deubiquitinase inhibitor
P005091
A selective inhibitor of ubiquitin-specific protease 7
Vialinin A
A natural immunosuppressant from fungi
USP7/USP47 inhibitor
A dual inhibitor of USP7 and USP47
ML364
An inhibitor of USP2
GNE-6776
GNE-6776 is a potent, non-covalent, selective and orally bioavailable inhibitor of USP7 with IC50 of 1.34 μM and 0.61 μM for full length USP7 and USP7 catalytic domain, respectively.
GNE-6640
An inhibitor of USP7
FT827
FT827是选择性和共价的泛素特异性蛋白酶7(USP7)抑制剂,IC50值为52nM。
F1063-0967
A DUSP26 inhibitor
EOAI3402143
EOAI3402143 is a dose-dependent inhibitor of Usp9x, Usp24 and Usp5 that increases tumor cell apoptosis, and fully blocks or regresses myeloma tumors in mice.
Carbenoxolone
An 11β-HSD inhibitor