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Hydroxychloroquine-d4 (sulfate)
An internal standard for the quantification of hydroxychloroquine
CWHM-1552
CWHM-1552 是一种口服有效的恶性疟原虫抑制剂,对 3D7 和 Dd2 strain 的 IC50s 分别是 51 nM and 53 nM。
Dermaseptin TFA
Dermaseptin TFA 是从青蛙皮肤中分离出来的一种肽,在微摩尔浓度下表现出对细菌、真菌和原生动物强有力的抗菌 (antimicrobial) 活性。
Cycloguanil-d6 (hydrochloride)
A neuropeptide with diverse biological activities
13,21-Dihydroeurycomanone
13,21-Dihydroeurycomanone 是一种从 Eurycoma longifolia 根中分离出来的天然化合物,对恶性疟原虫和弓形虫具有抗寄生虫活性
Cytidine 3’-monophosphate
A ribonucleotide
Sphynolactone-7
An agonist of S. hermonthica ShHTL7
(S)-Purvalanol B
(S)-Purvalanol B 是 Purvalanol B 的 S 对映体。Purvalanol B 是细胞周期蛋白依赖性激酶抑制剂。
DDD107498
DDD107498 (DDD-498) 是一种有效的口服活性抗疟药,抑制寄生虫的多个生命周期阶段,对疟原虫的 EC50 为 1 nM。
Purfalcamine
Purfalcamine是一种具有口服活性,选择性的恶性疟原虫钙依赖性蛋白激酶1(PfCDPK1)抑制剂,IC50为17nM,EC50为230nM。Purfalcamine具有抗疟疾活性,可以引起疟原虫在裂殖体阶段的发育停滞。
Toltrazuril sulfoxide
Toltrazuril sulfoxide 是托曲脲短暂的中间代谢物 (intermediary metabolite),在体内可代谢为活性的托曲脲砜 (TZR-SO2)。Toltrazuril 是一种抗原生动物 (antiprotozoal agent) 试剂,作用于 Coccidia 球虫寄生虫。
DDD107498 succinate
DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.
PfDHODH-IN-2
PfDHODH-IN-2, a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (pfDHODH) inhibitor with an IC50 of 1.11 ?M, acting as an antimalarial agent which can be used for the research of malaria.
Chloroquine-d5 (phosphate)
An internal standard for the quantification of chloroquine
trans-β-Farnesene
A volatile sesquiterpene hydrocarbon with pheromonal and kairomonal activities