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Angiotensin Fragment 1-7 (acetate)
A type 1 angiotensin II receptor agonist
GSK726701A
GSK726701A是前列腺素E2受体4(EP4)的部分激动剂,pEC50为7.4。
GW-870086
GW-870086是一种有效的抗炎剂,为糖皮质激素受体(glucocorticoidreceptor)激动剂,在A549细胞中,抑制NFκB报告基因活性,pIC50值为10.1。
T6167923
T6167923是一种有效的、选择性的 MyD88 依赖性信号通路抑制剂。T6167923 直接与 MyD88 的 Toll/IL1 受体 (TIR) 结构域结合,破坏 MyD88 的同二聚体形成。T6167923 抑制 NF-κB 驱动的葡萄球菌肠毒素AP (SEAP) 活性,并且改善抗炎活性,对 IFN-γ,IL-1β,IL-6 和 TNF-α 的 IC50 分别为 2.7 μM,2.9 μM,2.66 μM 和 2.66 μM。
Lanraplenib succinate
A Syk inhibitor
1V209
1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.
YQ128
An NLRP3 inflammasome inhibitor
BMS 470539 (hydrochloride)
BMS 470539 (hydrochloride)是一种高效的选择性黑皮质素1受体(MC-1R)激动剂,在cAMP积累测定中,对人源和鼠源MC1R的EC50值分别为16.8和11.6nM。
Acitretin-d3
A neuropeptide with diverse biological activities
Pranlukast-d4
Prunetin
An isoflavone with diverse biological activities
Arjunolic Acid
A triterpene with diverse biological activities
AS-2444697 (hydrochloride)
An IRAK4 inhibitor
ASP7657
An EP4 receptor antagonist
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
An isomer of linoleic acid