我的订单
商品收藏
没有相关数据
筛选出 171 条数据,请点击查看商品详情
Afatinib N-Oxide
AfatinibN-Oxide是Afatinibdimaleate氧化降解过程中的杂质。Afatinibdimaleate是一种不可逆的EGFR家族抑制剂。
Simotinib
Simotinib 是一种选择性、特异性、口服生物利用度高的 EGFR 酪氨酸激酶抑制剂,IC50 为 19.9 nM。抗肿瘤活性。
Mavelertinib
Mavelertinib是一种选择性的,口服有效的且不可逆的EGFR酪氨酸激酶抑制剂(EGFRTKI),对Del,L858R和双重突变体T790M/L858R和T790M/Del的IC50值分别为5、4、12和3nM。Mavelertinib可用于非小细胞肺癌(NSCLC)的研究。
EMI48
EMI48是EMI1的衍生物,EMI48比EMI1对突变型EGFR具有更大的效力。EMI48抑制EGFR三重突变体。
CPL304110
CPL304110 是有效的、口服有效的、选择性的成纤维细胞生长因子受体 FGFR (1-3) 的抑制剂,其对 FGFR (1-3) 的 IC50 值分别为 0.75 nM、0.5 nM 和 3.05 nM。
CP-547632 hydrochloride
A potent inhibitor of VEGFR2 and bFGF
Afatinib impurity 11
Afatinib impurity 11 is an impurity of afatinib, an EGFR family inhibitor.
Mobocertinib succinate
An inhibitor of mutant EGFR and HER2 receptors
Theliatinib
Theliatinib (HMPL-309) is a highly potent EGFR inhibitor with Ki value of 0.05 nM against the wild type EGFR and IC50 values of 3 nM and 22 nM against EGFR and EGFR T790M/L858R mutant. It demonstrats 50 fold greater selectivity for EGFR compared to 72 oth
CAY10781
An NRP-1/VEGF-A interaction inhibitor
NH2-PEG5-OH
NH2-PEG5-OH是一种PROTAClinker,属于PEG类。NH2-PEG5-OH可用于合成PROTAC分子。NH2-PEG5-OH也是一种不可降解(non-cleavable)的含5个单元PEG的ADClinker,可用于合成抗体偶联药物(ADC)。
AMG-Tie2-1
A Tie2 and VEGFR2 inhibitor
AST5902 trimesylate
AST5902 is the principal metabolite of alflutinib both in vitro and in vivo, which exerts remarkable antineoplastic activity similar to alflutinib. AST5902 exhibits much weak CYP3A4 induction potential compared to alflutinib.
Vatalanib succinate
Potent VEGFR inhibitor; also aromatase inhibitor
BMS 605541
Potent VEGFR-2 inhibitor