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AZ82
An inhibitor of KIFC1
FRAX597
A PAK1, PAK2, and PAK3 inhibitor
Empesertib (BAY 1161909)
Empesertib (BAY1161909, Mps1-IN-5), a derivative of triazolopyridine, is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase with IC50 of <1 nM. Empesertib has potential antineoplastic activity.
Integrin Antagonists 27
IntegrinAntagonists27是一种小分子整合蛋白αvβ3拮抗剂,亲和力为18nM,用作抗癌剂。
MPS1/TTK Inhibitor
An inhibitor of Mps1/TTK
Ispinesib (SB-715992)
An Eg5 inhibitor
ADAMTS-5 Inhibitor
A disintegrin and metalloproteinase with thrombospondin motifs 5 inhibitor
Cevipabulin
An activator of microtubule polymerization
Docetaxel
Docetaxel是紫杉烷类抗有丝分裂化疗药物,IC50为0.2 μM。
Parbendazole (SKF 29044)
An inhibitor of microtubule assembly
PF-3758309
An inhibitor of PAK4
Paprotrain
A MKLP-2 inhibitor
α2β1 Integrin Ligand Peptide
α2β1 Integrin Ligand Peptide在细胞膜表面与 α2β1 整合素受体相互作用,进入细胞介导细胞外信号。α2β1 Integrin Ligand Peptide是一种潜在的胶原受体拮抗剂。
CK 869
An inhibitor of the Arp2/3 complex
Zaurategrast
Zaurategrast (CT7758) 是一种口服有效的 α4-integrin 抑制剂。